© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86337 refers to a laboratory test specifically designed to measure insulin antibody levels in the blood. This test is crucial for assessing the presence of various types of insulin antibodies, which can include human serum autoantibodies that target the body's own insulin, as well as antibodies that may react to exogenous insulin. Exogenous insulin can be derived from different sources, including animal insulin (such as pork or beef), recombinant DNA technology, or insulin analogues. The measurement of these antibodies is particularly significant in the context of diabetes management. It can help identify individuals who are at risk of developing type 1 diabetes mellitus, a condition characterized by the autoimmune destruction of insulin-producing beta cells in the pancreas. Furthermore, this test plays a vital role in differentiating between latent autoimmune diabetes in adults (LADA) and other forms of diabetes, such as type 2 diabetes or gestational diabetes. Additionally, monitoring insulin antibody levels can provide insights into the clinical progression of type 1 diabetes mellitus, aiding healthcare providers in making informed decisions regarding patient care. The test is performed by obtaining a blood sample through a procedure known as venipuncture, which is separately reportable, and the serum is then analyzed using a quantitative radioimmunoassay method.
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