CPT® Code 86510

Histoplasmosis is an infectious disease caused by the fungus Histoplasma capsulatum, which thrives in soil enriched with organic matter, particularly in areas contaminated by bat or bird droppings. This condition is particularly prevalent in the Central and Eastern United States, as well as in certain caves in Eastern Africa. The skin test for histoplasmosis is a diagnostic procedure used to evaluate the cellular immune response of individuals who may have been exposed to this fungus. During the test, a small amount of the fungal antigen is introduced into the skin through a pinprick. The immune system's reaction to this antigen is then monitored over a specified period. A positive result from the skin test can suggest either an active infection or a previous exposure to the fungus, indicating that the individual's immune system has recognized the pathogen. This test is crucial for diagnosing histoplasmosis, especially in individuals who may be at risk due to environmental exposure.