CPT® Code 86625

Official Description

Antibody; Campylobacter

Common Language Description

The CPT® Code 86625 refers to a laboratory test specifically designed to measure antibodies against Campylobacter, a type of spiral-shaped bacteria known to cause gastrointestinal infections in both humans and animals. This test is crucial for diagnosing infections that may lead to symptoms such as diarrhea, which can often be bloody, along with nausea, vomiting, abdominal pain, and fever. Campylobacter infections are particularly prevalent during the summer months and are typically characterized by isolated and sporadic outbreaks. The primary mode of transmission is through the ingestion of raw or undercooked meat and poultry, as well as foods that have been contaminated by these sources. Additionally, unpasteurized dairy products, contaminated drinking water, and contact with infected household pets can also result in human infections. A positive result for Campylobacter jejuni IgG antibodies indicates either a current or past infection with this bacterium. To perform this test, a blood sample is collected, which is reported separately through a venipuncture procedure. The serum obtained from the blood sample is then analyzed using a semi-quantitative indirect fluorescent antibody technique, allowing for the detection and measurement of the specific antibodies present in the patient's serum.

1. Indications

The antibody test for Campylobacter (CPT® Code 86625) is indicated for the following conditions:

Gastrointestinal Symptoms The test is performed when a patient presents with gastrointestinal symptoms such as diarrhea, which may be bloody, nausea, vomiting, abdominal pain, and fever, suggesting a possible Campylobacter infection.
Recent Exposure It is indicated for individuals who have had recent exposure to potential sources of Campylobacter, including raw or undercooked meat and poultry, unpasteurized dairy products, or contaminated drinking water.
Outbreak Investigation The test may be utilized during outbreak investigations to confirm cases of Campylobacter infection in affected populations.

2. Procedure

The procedure for testing Campylobacter antibodies involves several key steps:

Step 1: Patient Preparation Prior to the test, the patient may be advised to avoid certain medications or foods that could interfere with the results, although specific instructions may vary based on clinical judgment.
Step 2: Venipuncture A qualified healthcare professional performs a venipuncture to obtain a blood sample from the patient. This involves using a sterile needle to access a vein, typically in the arm, and collecting the blood into a designated collection tube.
Step 3: Serum Separation After collection, the blood sample is processed to separate the serum from the cellular components. This is typically done by centrifugation, which spins the sample at high speeds to facilitate the separation of serum.
Step 4: Testing The serum is then subjected to a semi-quantitative indirect fluorescent antibody test. This method involves adding specific reagents that bind to Campylobacter antibodies, allowing for their detection and measurement under a fluorescent microscope.
Step 5: Result Interpretation The results are interpreted by a qualified laboratory professional, who assesses the presence and levels of Campylobacter jejuni IgG antibodies, indicating either a current or past infection.

3. Post-Procedure

After the procedure, patients may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for this test, but patients should be advised to monitor the site for any unusual signs of infection, such as increased redness or swelling. Results from the Campylobacter antibody test are usually available within a few days, and healthcare providers will discuss the findings with the patient, including any necessary follow-up actions based on the results.

Short Descr	CAMPYLOBACTER ANTIBODY
Medium Descr	ANTIBODY CAMPYLOBACTER
Long Descr	Antibody; Campylobacter
Status Code	Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days	XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC)	9 - Not Applicable
Multiple Procedures (51)	9 - Concept does not apply.
Bilateral Surgery (50)	9 - Concept does not apply.
Physician Supervisions	09 - Concept does not apply.
Assistant Surgeon (80, 82)	9 - Concept does not apply.
Co-Surgeons (62)	9 - Concept does not apply.
Team Surgery (66)	9 - Concept does not apply.
Diagnostic Imaging Family	99 - Concept Does Not Apply
CLIA Waived (QW)	No
APC Status Indicator	Conditionally packaged laboratory tests
Type of Service (TOS)	5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS)	T1H - Lab tests - other (non-Medicare fee schedule)
MUE	1
CCS Clinical Classification	235 - Other Laboratory

90	Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.