CPT® Code 86628

The CPT® Code 86628 refers to the laboratory test for antibodies to Candida, a type of fungus that is typically found on the skin and in mucous membranes, including areas such as the vagina, mouth, and rectum. Under normal circumstances, Candida exists harmlessly; however, it can become pathogenic and lead to an infection known as Candidiasis or moniliasis when there is a disruption in the body's chemical balance. This disruption can occur in individuals who are taking antibiotics, those with weakened immune systems, and infants, making them particularly vulnerable to Candida infections. The infections are most commonly localized to areas such as the mouth, skin, nails, or vagina, but in more severe cases, they can affect the esophagus and gastrointestinal tract. In rare instances, Candida can enter the bloodstream, leading to systemic infections that may impact vital organs such as the kidneys, heart, lungs, eyes, or brain. To diagnose a Candida infection, various testing methods are employed, including immunodiffusion and enzyme-linked immunosorbent assay (ELISA). The ELISA method is particularly notable as it measures different classes of immunoglobulins—IgA, IgG, and IgM—each of which is reported separately, providing a comprehensive overview of the immune response to the Candida fungus.