Need help choosing the right code?
Ask CasePilot about procedures, modifiers, bundling, and coding guidance.
Try CasePilot© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86658 refers to a laboratory test that measures antibodies specific to enteroviruses, which include coxsackievirus, echovirus, and poliovirus. These viruses belong to the picornaviridae family and are known for their role in various infectious diseases. The test is performed on serum and/or cerebrospinal fluid (CSF) to assess the presence of antibodies that indicate an immune response to these viruses. Coxsackievirus is categorized into two groups, A and B, with multiple subtypes that can lead to a range of clinical manifestations. For instance, Coxsackievirus A is associated with herpangina and hand, foot, and mouth disease, while Coxsackievirus B is linked to more severe conditions such as epidemic pleurodynia, which presents with fever and pain. Echovirus infections can result in febrile illnesses and have been associated with meningitis and myositis. Poliovirus, known for its high infectivity, can lead to serious complications including paralysis. The testing process involves obtaining a blood sample through venipuncture and a CSF sample via lumbar puncture, both of which are reported separately. The CSF is analyzed for Coxsackievirus A and B and echovirus using complement fixation, while serum is evaluated for Coxsackievirus B, echovirus, and poliovirus through semi-quantitative serum neutralization. It is important to note that cross-reactivity among these enteroviruses may occur, and the virus with the highest titer is typically indicative of the infecting serotype.
© Copyright 2026 Coding Ahead. All rights reserved.
The procedure associated with CPT® Code 86658 is indicated for the evaluation of suspected enterovirus infections. The following conditions may warrant this laboratory test:
The procedure for CPT® Code 86658 involves several key steps to ensure accurate measurement of enterovirus antibodies:
After the procedure, patients may experience mild discomfort at the venipuncture or lumbar puncture sites. It is important to monitor for any adverse reactions, particularly following the lumbar puncture, which may include headache or back pain. The results of the antibody tests will be reviewed by the healthcare provider to determine the appropriate clinical management based on the presence of enterovirus antibodies. Follow-up may be necessary to discuss the findings and any further diagnostic or therapeutic steps that may be required.
| Short Descr | ENTEROVIRUS ANTIBODY | Medium Descr | ANTIBODY ENTEROVIRUS | Long Descr | Antibody; enterovirus (eg, coxsackie, echo, polio) | Status Code | Statutory Exclusion (from MPFS, may be paid under other methodologies) | Global Days | XXX - Global Concept Does Not Apply | PC/TC Indicator (26, TC) | 9 - Not Applicable | Multiple Procedures (51) | 9 - Concept does not apply. | Bilateral Surgery (50) | 9 - Concept does not apply. | Physician Supervisions | 09 - Concept does not apply. | Assistant Surgeon (80, 82) | 9 - Concept does not apply. | Co-Surgeons (62) | 9 - Concept does not apply. | Team Surgery (66) | 9 - Concept does not apply. | Diagnostic Imaging Family | 99 - Concept Does Not Apply | CLIA Waived (QW) | No | APC Status Indicator | Conditionally packaged laboratory tests | Type of Service (TOS) | 5 - Diagnostic Laboratory | Berenson-Eggers TOS (BETOS) | T1H - Lab tests - other (non-Medicare fee schedule) | MUE | 12 | CCS Clinical Classification | 235 - Other Laboratory |
| 90 | Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number. | 91 | Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient. | 59 | Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25. | 26 | Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number. |
|
Date
|
Action
|
Notes
|
|---|---|---|
| 1993-01-01 | Added | First appearance in code book in 1993. |
Get instant expert-level medical coding assistance.