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Official Description

Antibody; Leishmania

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86717 refers to a laboratory test specifically designed to measure antibodies against Leishmania, a parasitic organism. Leishmania is primarily found in tropical and subtropical regions, as well as Southern Europe, and is transmitted to humans through the bite of infected sand flies. The infection can manifest in two primary forms: cutaneous and visceral. The cutaneous form is marked by the development of skin sores or ulcers, which may become scabbed or crusted, and is often associated with swollen lymph nodes. In contrast, the visceral form of the disease occurs when the parasite invades internal organs such as the liver, spleen, and bone marrow. Symptoms of visceral leishmaniasis can vary widely; some individuals may remain asymptomatic, while others may experience significant clinical manifestations including fever, weight loss, enlargement of the spleen and liver, anemia, leukopenia, or thrombocytopenia. The presence of a positive IgG antibody titer in the test results indicates either a current or past infection with Leishmania. To perform this test, a blood sample is collected from the patient through a procedure known as venipuncture, which is reported separately. The serum obtained from the blood sample is then analyzed using a semi-quantitative immunoassay to determine the level of antibodies present.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The antibody test for Leishmania (CPT® Code 86717) is indicated for the following conditions:

  • Suspected Leishmaniasis Infection The test is performed when there is a clinical suspicion of Leishmaniasis, particularly in patients who have traveled to endemic regions or have been exposed to sand flies.
  • Evaluation of Symptoms It is indicated for patients presenting with symptoms such as skin sores, ulcers, fever, weight loss, or splenomegaly, which may suggest either cutaneous or visceral forms of the disease.
  • Monitoring Disease Progression The test may be used to monitor the immune response in patients diagnosed with Leishmaniasis, helping to assess the effectiveness of treatment.

2. Procedure

The procedure for conducting the Leishmania antibody test involves several key steps:

  • Step 1: Patient Preparation Prior to the test, the patient may be instructed to avoid certain medications or supplements that could interfere with the test results. It is essential to ensure that the patient is adequately informed about the procedure and its purpose.
  • Step 2: Venipuncture A qualified healthcare professional performs venipuncture to obtain a blood sample from the patient. This involves using a sterile needle to puncture a vein, typically in the arm, and collecting the blood into a designated collection tube. The procedure is performed under aseptic conditions to minimize the risk of infection.
  • Step 3: Serum Separation After the blood sample is collected, it is processed in the laboratory to separate the serum from the cellular components. This is typically done by centrifugation, which spins the sample at high speeds to separate the liquid serum from the blood cells.
  • Step 4: Immunoassay Testing The serum is then subjected to a semi-quantitative immunoassay, which detects the presence of IgG antibodies specific to Leishmania. This assay measures the concentration of antibodies, providing insight into the patient's immune response to the infection.
  • Step 5: Result Interpretation Once the testing is complete, the results are analyzed and interpreted by a qualified laboratory professional. A positive result indicates the presence of antibodies, suggesting current or past infection with Leishmania.

3. Post-Procedure

After the procedure, patients may experience minor discomfort or bruising at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care instructions required for this test, but patients should be advised to report any unusual symptoms or prolonged discomfort. The results of the test will be communicated to the healthcare provider, who will discuss the findings with the patient and determine any necessary follow-up actions or treatments based on the results.

Short Descr LEISHMANIA ANTIBODY
Medium Descr ANTIBODY LEISHMANIA
Long Descr Antibody; Leishmania
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 8
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
1993-01-01 Added First appearance in code book in 1993.
Code
Description
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