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Official Description

Antibody; Neisseria meningitidis

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86741 refers to a laboratory test specifically designed to measure antibodies against Neisseria meningitidis, a bacterium responsible for causing severe infections in the central nervous system and bloodstream. This bacterium is known for its highly contagious nature, primarily spreading through respiratory droplets found in saliva and mucus. The onset of symptoms associated with infections caused by N. meningitidis is typically sudden and can manifest as fever, headache, stiff neck, nausea, vomiting, skin rash, sensitivity to light, and confusion. The test focuses on detecting IgG antibodies, which include serogroups A, C, W-135, and Y. It serves a dual purpose: assessing the immune response following vaccination and evaluating individuals who may have an immune deficiency. Importantly, this test is not intended for diagnosing acute infections or determining serotype. To perform the test, a blood sample is collected through a separately reportable venipuncture, and the serum is analyzed using a quantitative multiplex bead assay, which allows for precise measurement of the antibody levels present in the sample.

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