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Official Description

Antibody; rotavirus

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86759 refers to a laboratory test specifically designed to measure antibodies against rotavirus. Rotavirus is a significant pathogen that primarily affects infants and young children, leading to gastrointestinal illnesses characterized by symptoms such as diarrhea, vomiting, fever, and abdominal pain. These symptoms can be severe and may result in dehydration, which sometimes necessitates hospitalization for appropriate treatment. The test evaluates different types of antibodies: a positive IgM antibody titer indicates a recent infection, while a positive IgG titer suggests a past infection. However, in infants, the presence of IgG may also indicate the passive transfer of maternal antibodies, complicating the interpretation of results. Additionally, a positive IgA antibody titer is typically observed during the recovery phase following an infection. To conduct this test, a blood sample is collected through a procedure known as venipuncture, which is reported separately. The serum obtained from the blood sample is then analyzed for the presence of IgG, IgM, and IgA antibodies using an indirect enzyme immunoassay technique, providing valuable information regarding the patient's immune response to rotavirus.

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