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Official Description

Antibody; Toxoplasma

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 86777 refers to a laboratory test specifically designed to identify antibodies against Toxoplasma gondii, a parasite that can infect various animals, including humans. This test is crucial for diagnosing toxoplasmosis, an infection that can arise from consuming undercooked or raw meats from infected animals or through exposure to feces from infected cats. While toxoplasmosis is often a mild disease that resolves without medical intervention, it poses significant risks for certain populations. For instance, pregnant women may experience severe consequences, such as blindness or brain damage in the fetus, while individuals with compromised immune systems may face life-threatening illnesses. The testing process typically involves analyzing a blood sample, although cerebrospinal fluid (CSF) may also be utilized in certain cases. The test identifies total antibodies, including both IgG and IgM, through methods such as enzyme-linked immunosorbent assay (ELISA) or chemiluminescent immunoassay. The presence of IgG antibodies generally indicates a past infection, while IgM antibodies, which are tested under CPT® Code 86778, suggest a current or recent infection. Overall, this test plays a vital role in the detection and management of toxoplasmosis, particularly in at-risk populations.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The CPT® Code 86777 is indicated for the following conditions and situations:

  • Screening for Toxoplasmosis This test is performed to screen individuals for past or present infections of Toxoplasma gondii, particularly in pregnant women or immunocompromised patients.
  • Diagnosis of Infection It aids in diagnosing toxoplasmosis in patients presenting with symptoms consistent with the infection, such as flu-like symptoms, lymphadenopathy, or ocular issues.
  • Monitoring Immunocompromised Patients The test is used to monitor patients with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy, who are at higher risk for severe toxoplasmosis.

2. Procedure

The procedure for CPT® Code 86777 involves several key steps to ensure accurate identification of Toxoplasma antibodies:

  • Sample Collection A blood sample is collected from the patient, typically via venipuncture. In some cases, cerebrospinal fluid (CSF) may be obtained if there is a suspicion of central nervous system involvement.
  • Laboratory Analysis The collected sample is then subjected to laboratory analysis using enzyme-linked immunosorbent assay (ELISA) or chemiluminescent immunoassay techniques. These methods are designed to detect the presence of total antibodies, including both IgG and IgM, against Toxoplasma gondii.
  • Result Interpretation After the analysis, the laboratory interprets the results. The presence of IgG antibodies typically indicates a past infection, while the detection of IgM antibodies suggests a current or recent infection. The results are then reported to the healthcare provider for further evaluation and management.

3. Post-Procedure

Post-procedure care for patients undergoing testing with CPT® Code 86777 is generally minimal, as the blood draw is a routine procedure. Patients may experience slight discomfort or bruising at the puncture site, which typically resolves quickly. It is important for healthcare providers to discuss the test results with patients, particularly if the results indicate a current or recent infection, as this may necessitate further clinical evaluation or treatment. Additionally, patients should be informed about the significance of the results, especially in the context of pregnancy or immunocompromised status, to ensure appropriate follow-up care and management.

Short Descr TOXOPLASMA ANTIBODY
Medium Descr ANTIBODY TOXOPLASMA
Long Descr Antibody; Toxoplasma
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 2
CCS Clinical Classification 235 - Other Laboratory
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
26 Professional component: certain procedures are a combination of a physician or other qualified health care professional component and a technical component. when the physician or other qualified health care professional component is reported separately, the service may be identified by adding modifier 26 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
91 Repeat clinical diagnostic laboratory test: in the course of treatment of the patient, it may be necessary to repeat the same laboratory test on the same day to obtain subsequent (multiple) test results. under these circumstances, the laboratory test performed can be identified by its usual procedure number and the addition of modifier 91. note: this modifier may not be used when tests are rerun to confirm initial results; due to testing problems with specimens or equipment; or for any other reason when a normal, one-time, reportable result is all that is required. this modifier may not be used when other code(s) describe a series of test results (eg, glucose tolerance tests, evocative/suppression testing). this modifier may only be used for laboratory test(s) performed more than once on the same day on the same patient.
GA Waiver of liability statement issued as required by payer policy, individual case
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
X5 Diagnostic services requested by another clinician: for reporting services by a clinician who furnishes care to the patient only as requested by another clinician or subsequent and related services requested by another clinician; this modifier is reported for patient relationships that may not be adequately captured by the above alternative categories; reporting clinician service examples include but are not limited to, the radiologist's interpretation of an imaging study requested by another clinician
Date
Action
Notes
1993-01-01 Added First appearance in code book in 1993.
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