CPT® Code 86813

Human leukocyte antigen (HLA) typing is a laboratory procedure that identifies specific antigens present on the surface of cells, particularly those involved in the immune response. This process focuses on the A, B, or C antigens, which are critical for determining tissue compatibility in various medical contexts. HLA typing is essential for identifying individuals who may be susceptible to certain diseases, as well as for assessing compatibility between potential stem cell, bone marrow, or solid organ transplant donors and recipients. Additionally, HLA typing plays a significant role in determining eligibility for specific vaccine or immunotherapy treatments. The antigens are categorized into Class I and Class II alleles, with current testing methods available for assessing susceptibility to diseases such as ankylosing spondylitis through HLA-B27 DNA typing. Other tests, including HLA-A, HLA-B, and HLA-C DNA typing, are utilized to evaluate the risk of autoimmune disorders and to ensure proper tissue matching for transplants. It is important to note that CPT® Code 86812 should be used when testing for a single antigen, while CPT® Code 86813 is designated for cases where multiple HLA antigens are analyzed.