© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 86941 refers to a laboratory test that screens a unit of blood for the presence of hemolysins and cold agglutinins, specifically when the sample is incubated during the testing process. Hemolysins are antibodies that can cause the destruction of red blood cells, leading to hemolytic reactions, which can be dangerous during blood transfusions. Cold agglutinins, on the other hand, are antibodies that can agglutinate red blood cells at lower temperatures, potentially complicating the identification of blood group antigens. This screening is crucial prior to transfusion to ensure the safety and compatibility of the blood being administered to patients. The incubation of the sample during the test is a key aspect of this procedure, as it allows for the optimal detection of these potentially harmful substances, thereby reducing the risk of transfusion-related complications.
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