CPT® Code 87501

Infectious agent detection by nucleic acid (DNA or RNA); influenza virus, includes reverse transcription, when performed, and amplified probe technique, each type or subtype

The CPT® Code 87501 refers to a diagnostic test that detects the presence of influenza virus by analyzing nucleic acids, specifically DNA or RNA. This test is crucial for identifying the specific type or subtype of influenza present in a laboratory specimen. Influenza viruses are categorized into two main types: type A and type B, each of which can be further divided into various subtypes. For instance, type A includes subtypes such as H1N1, H3N2, and H5N1. The process of nucleic acid detection involves extracting the genetic material from the specimen, which may include blood or other bodily fluids. The test utilizes reverse transcription, if applicable, along with an amplified probe technique to accurately identify the influenza virus. The method typically employed is reverse transcription polymerase chain reaction (RT-PCR), which amplifies the extracted DNA or RNA from specific strains of the influenza virus. This amplification allows for the sizing and analysis of the genetic fragments, leading to the identification of the specific types or subtypes of influenza present. For billing purposes, CPT® Code 87501 is used for each individual type or subtype detected, while multiplex testing for the first two types or subtypes is coded with 87502, and any additional types or subtypes beyond the first two are coded with 87503.