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Official Description

Infectious agent genotype analysis by nucleic acid (DNA or RNA); cytomegalovirus

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 87910 refers to the process of conducting an infectious agent genotype analysis specifically for cytomegalovirus (CMV) using nucleic acid techniques, which can involve either DNA or RNA. This procedure is particularly significant in the context of patients who have tested positive for a CMV infection. CMV is a prevalent virus that typically remains asymptomatic in individuals with healthy immune systems. However, in patients with compromised immune systems, such as organ transplant recipients or individuals living with HIV, CMV can lead to severe complications due to its ability to replicate unchecked. The genotype analysis involves amplifying specific segments of the viral DNA, which enhances the ability to detect and identify the virus's genetic makeup. This identification is crucial as it can yield valuable prognostic information and guide healthcare providers in selecting appropriate antiviral therapies tailored to the specific genotype of the virus present in the patient. The procedure requires obtaining a blood sample, which is performed through a venipuncture that is reported separately. The analysis of the serum or plasma is typically conducted using advanced techniques such as polymerase chain reaction (PCR) or sequencing methods, which are essential for accurate genotyping of the virus.

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