CPT® Code 88147

Cytopathology smears, specifically for cervical or vaginal specimens, are critical diagnostic tests used to identify cellular changes that may indicate the presence of disease. This examination is particularly important for detecting conditions such as cervical dysplasia and in situ carcinoma, which can progress to invasive malignancies if not monitored and treated appropriately. Commonly known as a Papanicolaou (PAP) smear, this procedure involves the collection of cells from the endocervix using specialized tools like a brush or stick. Once collected, the specimen is prepared on a slide and coverslipped for analysis. The innovative aspect of CPT® Code 88147 is the use of an automated screening system, which operates under the supervision of a physician. This system employs advanced technology, including an automated microscope, a full-color camera, and high-speed image-processing capabilities, to screen the slides for any abnormalities in the cell structure. The automated system identifies and marks abnormal cells or clusters, storing these images for further evaluation. Following this automated screening, a technician reviews the results under the supervision of a physician, ensuring that any potential issues are accurately assessed. This process is essential for timely diagnosis and intervention, as abnormal findings may lead to recommendations for additional testing or more frequent monitoring of the patient's condition.