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Official Description

Cytopathology, slides, cervical or vaginal; with manual screening and computer-assisted rescreening under physician supervision

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

CPT® Code 88152 refers to the process of cytopathology specifically for cervical or vaginal specimens. This procedure involves the examination of slides that have been prepared from Papanicolaou (PAP) smears, which are critical for detecting cellular changes that may indicate disease. The examination is conducted under physician supervision and includes both manual screening and computer-assisted rescreening. The PAP smear is a vital screening tool used to identify abnormalities such as cervical dysplasia and in situ carcinoma, which are precursors to invasive cancer. The procedure begins with the collection of cells from the endocervix using a specialized instrument, such as a brush or stick. These cells are then smeared onto a glass slide, fixed to preserve the cellular structure, and sent to a cytology laboratory for further analysis. In the lab, the slide is stained to enhance visibility under a microscope. A trained technician manually screens the slide for any abnormalities, identifying any abnormal cells or clusters. The unique aspect of CPT® Code 88152 is the integration of computer-assisted technology, which aids in the rescreening process. The computer is designed to detect suspicious single cells and abnormal structures, providing a second layer of analysis. The technician reviews the findings from both the manual and computer-assisted screenings, ensuring a comprehensive evaluation of the specimen under the supervision of a physician. This thorough approach is essential for accurate diagnosis and subsequent management of potential cervical pathologies.

© Copyright 2026 Coding Ahead. All rights reserved.

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