CPT® Code 88167

Cytopathology, slides, cervical or vaginal (the Bethesda System); with manual screening and computer-assisted rescreening using cell selection and review under physician supervision

The CPT® Code 88167 refers to a specific cytopathology procedure involving the analysis of cervical or vaginal slides using the Bethesda System. This procedure is commonly known as a Papanicolaou (PAP) smear, which is a screening test designed to detect abnormalities in cervical cells that could indicate the presence of precancerous conditions or cervical cancer. The Bethesda System is the standard reporting framework utilized in the United States for interpreting PAP smear results, providing a structured approach to categorize findings based on the adequacy of the sample and the presence of any cellular abnormalities. The results can indicate various conditions, including benign changes, atypical squamous cells of undetermined significance (ASCUS), atypical glandular cells of undetermined significance (AGCUS), dysplasia, or squamous intraepithelial lesions (SIL), which are further classified into low-grade (LGSIL) and high-grade (HGSIL) lesions, as well as carcinoma. During the procedure, cells are collected from the endocervix using a specialized instrument, such as a brush or stick, and then smeared onto a glass slide. The slide is subsequently fixed using either a spray or immersion method and is then covered with a coverslip. Once prepared, the slide is sent to a cytology laboratory where it undergoes staining to enhance the visibility of the cells under a microscope. A trained technician performs the initial screening of the slide, looking for any signs of abnormalities. In the case of CPT® Code 88167, the technician conducts a manual screening followed by a computer-assisted rescreening process. This involves the use of computer technology to identify suspicious single cells and abnormal cell structures, which the technician then reviews in conjunction with the manual findings. The comprehensive analysis ensures that any potential abnormalities are accurately identified and interpreted, with findings communicated to the treating physician for further action if necessary.