© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 88177 pertains to cytopathology, specifically focusing on the evaluation of fine needle aspirates (FNAs). This procedure involves an immediate cytohistologic study aimed at determining the adequacy of the specimen for diagnostic purposes. In simpler terms, a fine needle aspiration is conducted to collect fluid or tissue samples from a specific site in the body. Following an initial evaluation episode, which is also reportable separately, additional evaluations may be performed on the same specimen to assess whether it is adequate for diagnosis. During this process, the collected cells are placed on a slide, where they typically form clusters of approximately ten cells each. A smear is created by placing another slide on top of the first, and various stains may be applied to enhance the visibility of cellular details. The physician then examines the specimen under a microscope to check for signs of disease, including malignancy. The accuracy of the diagnosis improves significantly when there are at least six cell clusters available for review. If the sample is found to be inadequate, the physician may decide to repeat the aspiration procedure. It is important to report code 88177 for each additional separate evaluation episode conducted on a specimen from the same site after the initial evaluation has been completed.
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