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Official Description

Flow cytometry, interpretation; 9 to 15 markers

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Flow cytometry is a sophisticated laboratory technique utilized to analyze the characteristics of cells or particles in a fluid as they pass through a laser or other light source. This method is particularly effective for measuring various cell surface, cytoplasmic, or nuclear markers in samples such as whole blood, serum, and bone marrow. The process involves the use of specific antibodies that bind to target antigens on the cells, allowing for the identification and quantification of different cell types based on their unique markers. The flow cytometer, a specialized instrument, is controlled by a computer program that manages data acquisition and presents the results in the form of histograms and graphs. These visual representations facilitate the interpretation of the data by highlighting the separation of cells based on their physical and chemical properties, which are often enhanced by the use of fluorescent dyes. The physician interprets the collected data, providing a comprehensive analysis that includes the identification of the instruments and software utilized during the testing process. A written report detailing the findings is generated, which is essential for further clinical decision-making. The CPT® code 88188 specifically pertains to the interpretation of flow cytometry results involving 9 to 15 markers, distinguishing it from other codes that correspond to different ranges of markers analyzed.

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