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Official Description

Nasal smear for eosinophils

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A nasal smear for eosinophils is a laboratory procedure designed to identify the presence of eosinophils, which are a specific type of white blood cell involved in the body's immune response. This procedure is particularly relevant in the context of diagnosing allergic conditions, such as allergic rhinitis. During the test, nasal secretions are collected through a swab inserted into each nostril, targeting the area near the septum and nasal floor. The swab is held in place for a duration of 15 to 30 seconds, or until a cough reflex is elicited, ensuring an adequate sample is obtained. Alternatively, the patient may be instructed to blow their nose into a piece of waxed paper or cellophane to collect the secretions. Once collected, the nasal secretions are placed on a glass slide and subjected to a staining process. This staining allows for the visualization of eosinophils when the slide is examined under a light microscope. The laboratory technician counts the number of eosinophils present in the sample and reports the findings, which can aid in confirming a diagnosis of allergic rhinitis or other related conditions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The nasal smear for eosinophils is indicated for the evaluation of various allergic conditions. The primary indications for performing this procedure include:

  • Allergic Rhinitis - The procedure is commonly performed to support the diagnosis of allergic rhinitis, a condition characterized by an allergic response that leads to symptoms such as sneezing, nasal congestion, and runny nose.
  • Other Allergic Conditions - It may also be indicated in the assessment of other allergic disorders where eosinophil levels may be relevant.

2. Procedure

The procedure for obtaining a nasal smear for eosinophils involves several key steps, which are detailed as follows:

  • Step 1: Sample Collection - The first step involves collecting nasal secretions. This can be achieved by inserting a sterile swab into each nostril, specifically targeting the area near the septum and nasal floor. The swab should be held in place for a duration of 15 to 30 seconds, or until a cough reflex is triggered, which indicates that an adequate sample has been obtained. Alternatively, the patient may be asked to blow their nose into a piece of waxed paper or cellophane to gather the nasal secretions.
  • Step 2: Slide Preparation - After the nasal secretions are collected, a small portion of the sample is placed onto a clean glass slide. This step is crucial for preparing the sample for microscopic examination.
  • Step 3: Staining - The sample on the slide is then stained using appropriate laboratory techniques. Staining is essential as it enhances the visibility of eosinophils under the microscope, allowing for accurate counting and assessment.
  • Step 4: Microscopic Examination - The stained slide is examined under a light microscope by a trained laboratory technician. During this examination, the technician counts the number of eosinophils present in the sample, which is a critical component of the diagnostic process.
  • Step 5: Reporting Results - Finally, the findings from the microscopic examination are documented and reported. The results will indicate the eosinophil count, which can provide valuable information for diagnosing allergic conditions.

3. Post-Procedure

Post-procedure care for a nasal smear for eosinophils is generally minimal, as the procedure is non-invasive and does not typically require any special recovery measures. Patients may resume their normal activities immediately following the test. However, it is important for healthcare providers to inform patients about potential mild discomfort during the sample collection process, such as nasal irritation or a brief cough reflex. The results of the nasal smear will be communicated to the patient in a timely manner, and any necessary follow-up or additional testing will be discussed based on the findings.

Short Descr NASAL SMEAR FOR EOSINOPHILS
Medium Descr NASAL SMEAR EOSINOPHILS
Long Descr Nasal smear for eosinophils
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 206 - Microscopic examination (bacterial smear, culture, toxicology)
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GW Service not related to the hospice patient's terminal condition
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Pre-1990 Added Code added.
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