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Official Description

Dengue vaccine, quadrivalent, live, 3 dose schedule, for subcutaneous use

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 90587 refers to the quadrivalent dengue vaccine, which is a live attenuated vaccine designed for subcutaneous administration. Unlike immune globulins that offer short-term, passive immunity, this vaccine provides active, long-term immunity. It achieves this by exposing the recipient's immune system to modified versions of the dengue virus, prompting the body to produce its own antibodies. This immunological response enables the body to "remember" how to generate antibodies when it encounters the dengue virus in the future. Dengue fever, also known as breakbone fever, is a mosquito-borne illness characterized by symptoms such as high fever, rash, and intense muscle and joint pain. In severe cases, it can lead to life-threatening complications, including bleeding and shock. The quadrivalent dengue vaccine specifically targets the four serotypes of the dengue virus, known as DENV 1 through DENV 4. The vaccination schedule consists of three doses administered at intervals of 0, 6, and 12 months. It is important to note that this code is used solely to report the vaccine product itself, while the administration of the vaccine should be reported separately.

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