© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 90647 refers to the Haemophilus influenzae type b (Hib) vaccine, specifically the PRP-OMP conjugate formulation, which is administered via intramuscular injection. Vaccines, unlike immune globulins that offer short-term, passive immunity, are designed to provide active, long-term immunity. This is achieved by introducing altered versions of specific pathogens, such as viruses or bacteria, into the recipient's body. The immune system then responds by producing its own antibodies, which enables the body to "remember" how to combat the pathogen upon future exposure. Haemophilus influenzae type b is particularly concerning for children under the age of five, as it can lead to severe health complications, including pneumonia, significant swelling of the throat, infections in the joints and bones, and meningitis, which can result in lasting effects such as brain damage and hearing loss. The code 90647 specifically denotes the administration of the PRP-OMP conjugate Hib vaccine following a 3-dose schedule, while code 90648 is designated for the PRP-T conjugate vaccine administered in a 4-dose schedule. It is important to note that these codes are strictly for reporting the vaccine product used in immunization efforts.
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