CPT® Code 90678

The CPT® Code 90678 refers to the respiratory syncytial virus (RSV) vaccine, specifically the preF, subunit, bivalent formulation intended for intramuscular use. This vaccine, developed by Pfizer, is designed to provide immunization against severe respiratory illnesses caused by RSV, particularly targeting vulnerable populations such as adults aged 60 and older, as well as infants through maternal immunization during pregnancy. RSV is a prevalent virus that leads to significant respiratory illness, especially during the fall and winter months when respiratory infections are most common. The vaccine leverages the crystal structure of the prefusion F protein, which is a crucial component of the viral fusion protein that RSV utilizes to invade human cells. By focusing on this specific form of the viral protein, the vaccine aims to stimulate the production of protective antibodies that effectively target RSV. The bivalent nature of this vaccine means it contains two preF proteins, enhancing the immune response against both RSV A and B strains, thereby optimizing protection. It is important to note that this code is used solely for reporting the vaccine product itself, and the administration of the vaccine via intramuscular injection should be reported separately.