CPT® Code 90733

The CPT® Code 90733 refers to the Meningococcal polysaccharide vaccine, specifically targeting serogroups A, C, Y, and W-135, known as quadrivalent meningococcal polysaccharide vaccine (MPSV4). This vaccine is designed for subcutaneous administration, meaning it is injected into the fatty tissue just beneath the skin. Unlike immune globulins, which offer short-term, passive immunity, vaccines like MPSV4 provide active, long-term immunity. This is achieved by exposing the recipient's immune system to altered forms of the bacteria, prompting the body to produce its own antibodies. Consequently, the immune system retains a memory of how to generate these antibodies upon future exposure to the same antigens. The MPSV4 vaccine is crucial in protecting against meningococcal disease, a severe illness caused by the bacterium Neisseria meningitidis. This pathogen is transmitted through respiratory secretions and can lead to serious health complications, including septicemia and meningitis, which may result in shock, coma, death, or long-term effects such as hearing loss or brain damage. There are 13 identified serogroups of Neisseria meningitidis, with six being responsible for the majority of global disease cases. The MPSV4 vaccine specifically protects against serogroups A, C, W-135, and Y, and is recommended for individuals aged 2 years and older. Importantly, this vaccine is composed of the outer polysaccharide capsule of the bacteria and does not contain any live virus, ensuring safety during administration. It is essential to note that this code pertains solely to the supply of the vaccine; the administration of the injection is reported separately.