© Copyright 2026 American Medical Association. All rights reserved.
Coronary thrombolysis is a medical procedure aimed at dissolving blood clots that obstruct coronary arteries, which can lead to serious cardiovascular events such as heart attacks. The procedure described by CPT® Code 92975 involves the direct administration of a thrombolytic agent through an intracoronary infusion. This method is typically performed when a patient presents with acute coronary syndrome, characterized by symptoms such as chest pain, shortness of breath, or other signs of myocardial ischemia. The procedure begins with the insertion of a catheter from a major access vessel, commonly the femoral or brachial artery, which is then navigated to the site of the thrombus within the coronary artery. Once the catheter is positioned correctly, a thrombolytic agent—such as streptokinase, alteplase, or reteplase—is infused directly into the artery to facilitate the breakdown of the clot. Following the infusion, contrast material is injected to conduct a selective coronary angiography, allowing the physician to visualize the artery and confirm that the thrombus has been effectively dissolved and that blood flow is restored. This procedure is critical in managing acute coronary events and improving patient outcomes by restoring perfusion to the heart muscle.
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