© Copyright 2026 American Medical Association. All rights reserved.
The ergonovine provocation test, identified by CPT® Code 93024, is a diagnostic procedure utilized to assess the cause of chest pain in patients who have no signs of atherosclerotic coronary artery disease or other coronary abnormalities as determined by arteriography. This test is particularly valuable in distinguishing between chest pain resulting from coronary artery spasm and that associated with esophageal spasm. During the procedure, ergonovine, which is also known as ergometrine or Methergine, is administered intravenously to the patient in a controlled manner. The administration begins with an initial dose of 0.1 mg, followed by incremental doses every five minutes until the patient reports chest pain. Throughout the test, the patient is continuously monitored via electrocardiography (ECG) to detect any changes that may indicate coronary artery spasm. If the ECG shows alterations consistent with spasm, the chest pain is classified as cardiac in origin, specifically spasm-induced angina. Conversely, if no significant ECG changes are observed, the pain is attributed to esophageal spasm. Upon the onset of pain, immediate intervention is provided to alleviate the spasm, ensuring patient safety and comfort during the evaluation process.
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