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Official Description

Direct nasal mucous membrane test

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The Direct Nasal Mucous Membrane Test, identified by CPT® Code 95065, is a diagnostic procedure primarily utilized for the evaluation of allergic rhinitis. This test, often referred to as a nasal challenge or nasal challenge/provocation test, involves the direct application of a suspected allergen to the nasal mucous membrane. The procedure is designed to assess the patient's allergic response to specific antigens. During the test, an applicator is used to deliver the allergen directly to the nasal mucosa, where the physician observes the immediate effects. Key indicators of an allergic reaction may include symptoms such as redness, itching, and increased mucus production. Following the test, the physician is responsible for providing a written interpretation that details the specific allergens tested and documents the patient's observed responses, which is crucial for accurate diagnosis and subsequent management of allergic conditions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The Direct Nasal Mucous Membrane Test is indicated for the evaluation of allergic rhinitis, particularly when there is a need to identify specific allergens that may be contributing to the patient's symptoms. This test is particularly useful in cases where the patient presents with signs of nasal allergies, and there is a suspicion of a particular antigen causing the allergic response.

  • Allergic Rhinitis The primary indication for this test is to evaluate patients who exhibit symptoms of allergic rhinitis, such as sneezing, nasal congestion, and runny nose, which may be triggered by environmental allergens.

2. Procedure

The Direct Nasal Mucous Membrane Test involves several key procedural steps that ensure accurate delivery of the allergen and observation of the patient's response.

  • Step 1: Preparation The physician prepares for the test by selecting the appropriate allergen(s) based on the patient's history and symptoms. The patient is informed about the procedure, and consent is obtained.
  • Step 2: Application of Allergen Using a specialized applicator, the physician delivers the suspected allergen directly to the nasal mucous membrane. This step is critical as it allows for the direct observation of the mucosal response to the allergen.
  • Step 3: Observation After the application, the physician closely monitors the patient for any immediate allergic reactions. Symptoms such as redness, itching, and increased mucus production are noted, as these are indicative of an allergic response.
  • Step 4: Documentation Following the observation period, the physician documents the findings, including the specific allergen(s) tested and the patient's response. This written interpretation is essential for further evaluation and management of the patient's allergic condition.

3. Post-Procedure

Post-procedure care for the Direct Nasal Mucous Membrane Test typically involves monitoring the patient for any delayed allergic reactions. Patients may be advised to avoid exposure to known allergens and to report any unusual symptoms following the test. The physician will review the results with the patient and discuss potential management strategies based on the identified allergens and the severity of the allergic response observed during the test.

Short Descr DIR NSL MUCOUS MEMBRANE TEST
Medium Descr DIRECT NASAL MUCOUS MEMBRANE TEST
Long Descr Direct nasal mucous membrane test
Status Code Active Code
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 3 - Technical Component Only Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 03 - Procedure must be performed under the personal supervision of physician.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator STV-Packaged Codes
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 1
CCS Clinical Classification 173 - Other diagnostic procedures on skin and subcutaneous tissue
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
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Notes
2025-01-01 Changed Short Description changed.
Pre-1990 Added Code added.
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