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Code deleted, to report use 96446

Official Description

Chemotherapy administration into peritoneal cavity, requiring and including peritoneocentesis

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

CPT® Code 96445 refers to the administration of chemotherapy directly into the peritoneal cavity, which is the space within the abdomen that houses various organs. This procedure is significant in the treatment of certain cancers, as it allows for localized delivery of chemotherapy agents, potentially increasing the effectiveness of the treatment while minimizing systemic exposure. The term "peritoneocentesis" included in the description indicates that the procedure requires the insertion of a needle through the abdominal wall to access the peritoneal cavity. This step is crucial as it facilitates the administration of the chemotherapy directly into the targeted area, ensuring that the medication can act on cancer cells present in the abdominal cavity. The procedure is typically performed in a clinical setting by a qualified healthcare professional, and it is essential for medical coders and billers to understand the specifics of this code to ensure accurate billing and compliance with coding guidelines.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure associated with CPT® Code 96445 is indicated for patients who require localized chemotherapy treatment for specific abdominal cancers. The following conditions may warrant the use of this procedure:

  • Abdominal Cancers Chemotherapy administration into the peritoneal cavity is often indicated for patients with cancers that have spread to the abdominal area, such as ovarian cancer or peritoneal carcinomatosis.
  • Recurrent Cancer Patients experiencing recurrence of cancer in the abdominal cavity may benefit from this localized treatment approach to target residual cancer cells effectively.
  • Palliative Care In some cases, this procedure may be performed as part of palliative care to alleviate symptoms associated with advanced cancer in the abdomen.

2. Procedure

The procedure for CPT® Code 96445 involves several critical steps to ensure safe and effective chemotherapy administration into the peritoneal cavity. Each step is essential for the successful execution of the procedure:

  • Step 1: Preparation The healthcare provider prepares the patient for the procedure by explaining the process, obtaining informed consent, and ensuring that the patient is in a comfortable position, typically lying down. Sterile techniques are employed to minimize the risk of infection.
  • Step 2: Peritoneocentesis The provider performs peritoneocentesis, which involves the insertion of a needle through the abdominal wall into the peritoneal cavity. This step is crucial as it allows access for the chemotherapy administration. The area is usually cleaned with an antiseptic solution, and local anesthesia may be administered to reduce discomfort.
  • Step 3: Chemotherapy Administration Once access to the peritoneal cavity is established, the chemotherapy agent is carefully administered through the catheter or needle. The dosage and type of chemotherapy used will depend on the specific treatment plan established by the healthcare provider.
  • Step 4: Monitoring After the administration of chemotherapy, the patient is monitored for any immediate adverse reactions or complications. Vital signs may be checked, and the healthcare team will observe the patient for signs of discomfort or distress.
  • Step 5: Post-Procedure Care Following the procedure, the healthcare provider will provide instructions for post-procedure care, including signs of potential complications to watch for and follow-up appointments for further treatment or evaluation.

3. Post-Procedure

Post-procedure care for patients who have undergone chemotherapy administration into the peritoneal cavity is essential for ensuring a safe recovery. Patients are typically advised to rest and may be monitored for a short period in a clinical setting to observe for any immediate side effects or complications. It is important for patients to report any unusual symptoms, such as increased abdominal pain, fever, or signs of infection, to their healthcare provider promptly. Follow-up appointments are usually scheduled to assess the effectiveness of the treatment and to plan any additional therapies that may be necessary. Patients may also receive guidance on managing side effects associated with chemotherapy, including nausea or fatigue, as part of their comprehensive care plan.

Short Descr CHEMOTHERAPY, INTRACAVITARY
Medium Descr CHEMOTX ADMN PRTL CAVITY REQ&W/PRITONEOCNTS
Long Descr Chemotherapy administration into peritoneal cavity, requiring and including peritoneocentesis
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Significant Procedure, Not Discounted When Multiple
Type of Service (TOS) 1 - Medical Care
Berenson-Eggers TOS (BETOS) P7B - Oncology - other
MUE Not applicable/unspecified.
CCS Clinical Classification 224 - Cancer chemotherapy
Date
Action
Notes
2011-01-01 Deleted Code deleted, to report use 96446
1990-01-01 Added Code added.
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