CPT® Code 96542

CPT® Code 96542 refers to the procedure of administering chemotherapy injections directly into the subarachnoid or intraventricular spaces of the central nervous system. This is achieved through a previously implanted subcutaneous reservoir, which allows for the delivery of one or more antineoplastic agents. The use of a subcutaneous reservoir is significant as it facilitates the administration of not only chemotherapy drugs but also monoclonal antibodies, biologic response modifiers, and other antineoplastic substances. Prior to the injection, the skin over the reservoir site is meticulously prepped to ensure a sterile environment. A specialized needle is then utilized to puncture the skin and access the reservoir. Once the needle is properly positioned, the reservoir is filled with the designated amount of the chemotherapy drug or other complex biologic agent. The delivery of the drug can be accomplished either by manually compressing the reservoir, which allows the drug to flow into the subarachnoid space or ventricles, or by employing a pump mechanism for more controlled administration. Once injected, the drug mixes with the cerebrospinal fluid, enabling it to circulate and reach the targeted site of the neoplasm effectively.