CPT® Code 96574

Debridement of premalignant hyperkeratotic lesion(s) (ie, targeted curettage, abrasion) followed with photodynamic therapy by external application of light to destroy premalignant lesions of the skin and adjacent mucosa with application and illumination/activation of photosensitizing drug(s) provided by a physician or other qualified health care professional, per day

Photodynamic therapy (PDT) is a medical procedure that utilizes photosensitive chemicals, also known as photoreactive agents, in conjunction with light exposure to effectively target and destroy premalignant lesions on the skin and adjacent mucosal areas. This therapy is particularly relevant for conditions characterized by hyperkeratosis, where there is an abnormal thickening of the outer layer of the skin. The process begins with the debridement of these hyperkeratotic lesions, which can be achieved through techniques such as targeted curettage or abrasion. This initial step is crucial as it prepares the lesions for the subsequent application of photoreactive chemicals. Once the lesions are adequately prepared, the chemicals are applied topically to the affected areas. Following this application, the area is illuminated with light of a specific wavelength, which activates the photosensitizing agents. This activation leads to a photochemical reaction that results in the destruction of the premalignant lesions. The procedure is performed by a physician or other qualified healthcare professional and is billed once per day, reflecting the comprehensive nature of the treatment provided during that time frame.