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Official Description

Photochemotherapy; psoralens and ultraviolet A (PUVA)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Photochemotherapy, specifically psoralens and ultraviolet A (PUVA), is a therapeutic procedure utilized to treat various severe photoresponsive dermatoses. This includes conditions such as psoriasis, eczema, vitiligo, and mycosis fungoides, which are skin disorders that respond positively to light therapy. The treatment involves the administration of psoralen, a medication that enhances the skin's sensitivity to UVA light, taken orally approximately two hours prior to exposure to the ultraviolet light. This preparatory step is crucial as it maximizes the effectiveness of the subsequent light therapy. In addition to PUVA, other forms of photochemotherapy, such as Goeckerman therapy, which combines coal tar and UVB light, or the use of petrolatum with UVB light, are also employed for similar conditions. After the psoralen is ingested or the topical agents like coal tar or petrolatum are applied, the patient is positioned in a specialized UVA or UVB light booth for a predetermined duration, tailored to the specific dermatosis being treated. The exposure time is critical and varies based on the individual condition and its severity. Post-treatment, any topical medications are carefully removed from the skin, followed by a thorough inspection of the treated areas, and dressings are applied as necessary to ensure proper healing and protection of the skin.

© Copyright 2026 Coding Ahead. All rights reserved.

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