© Copyright 2026 American Medical Association. All rights reserved.
High dose rate (HDR) electronic brachytherapy is an advanced treatment modality that utilizes an X-ray tube to deliver electronically generated photons as the radiation source, thereby eliminating the need for traditional radioactive isotopes. This innovative approach offers a refined and non-invasive method for treating non-melanoma skin cancer, particularly in areas where cosmetic outcomes are a significant concern. The procedure involves applying a precise, high dose rate of X-ray radiation directly to the cancerous lesion, which allows for effective treatment without the necessity for surgical intervention, extensive recovery time, or the complexities associated with handling radioactive materials. The technology is designed to target the cancerous tissue specifically, minimizing damage to the surrounding healthy tissue and significantly reducing the risk of scarring. The treatment can be conveniently administered in an office or clinical setting, such as by a dermatologist or radiation oncologist, and typically requires only a few brief visits. During these visits, the physician assesses the individual characteristics of the lesion, including its type, size, and location, to determine the appropriate treatment plan and prescribed dose of radiation. The portable X-ray generator is calibrated to deliver the specified dose, and a handheld X-ray tube applicator is positioned directly over the lesion for the designated duration, with minimal shielding applied as necessary. Each treatment session is divided into fractions, with each fraction reported separately, allowing for a tailored approach to patient care.
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