CPT® Code 0848T

Add-On Code

Digitization of glass microscope slides for in situ hybridization (eg, FISH), per specimen; initial single probe stain procedure (List separately in addition to code for primary procedure)

The CPT® Code 0848T refers to the process of digitizing glass microscope slides specifically for in situ hybridization procedures, such as fluorescence in situ hybridization (FISH). This procedure involves converting traditional glass slides into a digital format, allowing for the captured images to be stored either on a local computer server or within a cloud-based archive. The digitization process enhances the ability to examine the slides remotely, enabling pathologists to analyze the images without the need for physical access to the slides. Additionally, this digital format facilitates the use of computer algorithms that can assist in providing pathologic diagnoses, offering a distinct advantage over traditional direct visualization through a microscope. The digitization process is particularly relevant for stained slides of tissue biopsy specimens, which are prepared and analyzed using in situ hybridization techniques to identify specific target RNA or DNA sequences. When reporting this procedure, it is important to note that CPT® Code 0848T should be used for the initial single probe stain procedure. For subsequent procedures, such as additional single probe stains or multiplex probe stains, different codes (0849T and 0850T, respectively) are designated for accurate billing and documentation. This structured approach to coding ensures that each aspect of the digitization and staining process is appropriately captured for reimbursement and record-keeping purposes.