© Copyright 2026 American Medical Association. All rights reserved.
The CPT® Code 0850T refers to the process of digitizing glass microscope slides specifically for in situ hybridization procedures, such as fluorescence in situ hybridization (FISH). This procedure involves converting traditional glass slides into a digital format, allowing for the captured images to be stored either on a local computer server or within a cloud-based archive. The digitization of these slides facilitates further examination by pathologists who may be located remotely, as well as the use of advanced computer algorithms that assist in providing pathologic diagnoses. This method enhances the ability to analyze tissue biopsy specimens stained for specific target RNA or DNA, as it allows for a more comprehensive interpretation of the results in an increasingly image-based diagnostic environment. It is important to note that this code is specifically for each multiplex probe stain procedure and should be reported separately in addition to the code for the primary procedure. For instance, when a single probe stain preparation is performed, the corresponding code 0848T should be reported, while code 0849T is designated for each additional single probe stain. The use of code 0850T is essential for accurately capturing the digitization of each multiplex probe stain, ensuring proper documentation and billing for these advanced diagnostic services.
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