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Code deleted, see 15271-15278

Official Description

Acellular xenograft implant; each additional 100 sq cm, or each additional 1% of body area of infants and children, or part thereof (List separately in addition to code for primary procedure)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

An acellular xenograft implant is a specialized medical procedure utilized to cover wounds or skin defects. This type of implant is derived from skin or other tissues obtained from a different species, commonly porcine (pig). The term "acellular" indicates that the cells, cell debris, DNA, and RNA have been meticulously removed from the tissue. This process significantly reduces the likelihood of rejection by the recipient's immune system, allowing the implant to function effectively as a permanent solution for skin or soft tissue restoration. The composition of the acellular xenograft includes animal-derived collagen and elastin fibers, which undergo a cross-linking treatment to enhance their durability and prevent breakdown or reabsorption by the body. During the procedure, the xenograft implant is carefully removed from its packaging, tailored to fit the specific dimensions of the wound, and then applied to the prepared wound bed. It is secured in place using sutures to ensure proper adherence and facilitate healing. For billing purposes, CPT® Code 15430 is used for the initial coverage of up to 100 square centimeters in adults or up to 1% of total body surface area (TBSA) in infants and children, while CPT® Code 15431 is designated for each additional 100 square centimeters in adults or each additional 1% of TBSA in infants and children, or any part thereof.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The acellular xenograft implant is indicated for use in various clinical scenarios where there is a need to cover wounds or skin defects. The following conditions may warrant the application of this procedure:

  • Wound Coverage The procedure is performed to provide coverage for acute or chronic wounds that require additional support for healing.
  • Skin Defects It is indicated for the management of skin defects resulting from trauma, surgical excisions, or other dermatological conditions.
  • Burns The implant is utilized in the treatment of burn injuries, particularly when the affected area is extensive and requires skin replacement.
  • Congenital Defects It may be indicated for infants and children with congenital skin defects that necessitate surgical intervention and reconstruction.

2. Procedure

The procedure for applying an acellular xenograft implant involves several critical steps to ensure effective coverage and healing of the wound. Each step is essential for the successful application of the implant:

  • Preparation of the Wound Bed The first step involves thorough cleaning and debridement of the wound bed to remove any necrotic tissue, debris, or contaminants. This preparation is crucial to promote optimal adherence of the xenograft and to minimize the risk of infection.
  • Measurement and Cutting of the Implant Once the wound bed is adequately prepared, the acellular xenograft implant is removed from its sterile packaging. The clinician measures the dimensions of the wound and cuts the implant to the appropriate size and shape, ensuring that it adequately covers the entire defect.
  • Application of the Implant The cut xenograft is then carefully placed onto the prepared wound bed. It is important to position the implant correctly to ensure complete coverage and to facilitate healing.
  • Securing the Implant After placement, the xenograft is secured in position using sutures. This step is vital to maintain the stability of the implant and to prevent displacement during the healing process.

3. Post-Procedure

Post-procedure care is essential for the successful integration of the acellular xenograft implant and the healing of the wound. Patients are typically monitored for signs of infection or complications. It is important to keep the area clean and dry, and follow-up appointments may be scheduled to assess the healing process. The clinician may provide specific instructions regarding wound care, including how to manage any dressings and when to return for further evaluation. The expected recovery time can vary based on the size of the implant and the individual patient's healing response.

Short Descr APPLY ACELLULAR XGRAFT ADD
Medium Descr ACELLULAR XENOGRAFT IMPLANT EA 100 CM/1 PCT
Long Descr Acellular xenograft implant; each additional 100 sq cm, or each additional 1% of body area of infants and children, or part thereof (List separately in addition to code for primary procedure)
Status Code Carriers Price the Code
Global Days ZZZ - Code Related to Another Service
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 0 - No payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 0 - Payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 172 - Skin graft
Date
Action
Notes
2012-01-01 Deleted Code deleted, see 15271-15278
2011-01-01 Changed Guideline information changed.
2007-01-01 Changed Code description changed.
2006-01-01 Added Code added.
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Description
Code
Description
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