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Code deleted, see 15271-15278

Official Description

Acellular xenograft implant; first 100 sq cm or less, or 1% of body area of infants and children

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

An acellular xenograft implant is a specialized medical procedure utilized to cover wounds or skin defects. This type of implant is derived from skin or other tissues obtained from a different species, most commonly porcine (pig) tissue. The term "acellular" indicates that the cells, cell debris, DNA, and RNA have been meticulously removed from the tissue. This process significantly reduces the likelihood of rejection by the recipient's immune system, allowing the implant to function effectively as a permanent solution for skin or soft tissue restoration. The acellular xenograft is primarily composed of collagen and elastin fibers sourced from the animal tissue, which undergoes a cross-linking treatment. This treatment enhances the durability of the collagen, preventing it from being broken down and reabsorbed by the body. During the procedure, the xenograft implant is carefully removed from its packaging, and the implant sheet is tailored to fit the specific size and shape of the wound. It is then applied to the prepared wound bed and secured in place using sutures. The CPT® Code 15430 is designated for the use of this implant for the first 100 square centimeters or less in adults, or for 1% of the total body surface area (TBSA) in infants and children. For subsequent applications, the CPT® Code 15431 is utilized for each additional 100 square centimeters in adults or 1% of TBSA in infants and children, or any part thereof.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The acellular xenograft implant is indicated for use in various clinical scenarios where there is a need to cover a wound or skin defect. The following conditions may warrant the application of this procedure:

  • Wound Coverage The procedure is performed to provide coverage for acute or chronic wounds that require a biological dressing to promote healing.
  • Skin Defects It is indicated for the management of skin defects resulting from trauma, surgical excisions, or other dermatological conditions.
  • Burns The implant can be utilized in the treatment of burn injuries, particularly in cases where traditional grafting techniques may not be suitable.
  • Soft Tissue Reconstruction It is also indicated for soft tissue reconstruction in pediatric patients, where the use of a biocompatible material is essential for optimal healing.

2. Procedure

The procedure for applying an acellular xenograft implant involves several critical steps to ensure proper placement and effectiveness. Each step is outlined as follows:

  • Step 1: Preparation of the Wound Bed The first step involves thorough cleaning and debridement of the wound bed to remove any necrotic tissue, debris, or contaminants. This preparation is crucial to create an optimal environment for the implant to adhere and promote healing.
  • Step 2: Sizing the Implant Once the wound bed is adequately prepared, the acellular xenograft implant is removed from its packaging. The implant sheet is then carefully measured and cut to match the size and shape of the wound, ensuring complete coverage.
  • Step 3: Application of the Implant After sizing, the acellular xenograft is applied directly to the prepared wound bed. It is essential to position the implant correctly to maximize contact with the wound surface.
  • Step 4: Securing the Implant The final step involves securing the implant in place using sutures. This fixation is necessary to maintain the position of the graft and to prevent any movement that could compromise the healing process.

3. Post-Procedure

Post-procedure care is vital to ensure the success of the acellular xenograft implant. Patients are typically monitored for signs of infection or complications at the implant site. It is essential to keep the area clean and dry, and any dressings should be changed as directed by the healthcare provider. Patients may also receive instructions on how to care for the wound and when to return for follow-up evaluations. The expected recovery time can vary based on the individual’s overall health and the extent of the wound being treated. Regular follow-up appointments are necessary to assess the healing process and determine if additional interventions are required.

Short Descr APPLY ACELLULAR XENOGRAFT
Medium Descr ACELLULAR XENOGRAFT IMPLANT 1ST 100 CM/1 PCT
Long Descr Acellular xenograft implant; first 100 sq cm or less, or 1% of body area of infants and children
Status Code Active Code
Global Days 090 - Major Surgery
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 2 - Standard payment adjustment rules for multiple procedures apply.
Bilateral Surgery (50) 0 - 150% payment adjustment for bilateral procedures does NOT apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Discontinued Code
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) none
MUE Not applicable/unspecified.
CCS Clinical Classification 172 - Skin graft
Date
Action
Notes
2012-01-01 Deleted Code deleted, see 15271-15278
2007-01-01 Changed Code description changed.
2006-01-01 Added Code added.
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Description
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