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A tissue cultured allogeneic dermal substitute is a specialized medical product used to treat wounds or skin defects on the trunk, arms, or legs. This substitute is derived from human fibroblast cells, which are essential components of the skin that help in the healing process. The fibroblasts are typically sourced from newborn foreskin tissue and are cultured in a laboratory setting. During this process, the fibroblasts are seeded onto a bioabsorbable mesh scaffold, which serves as a framework for the cells to grow and multiply. As the fibroblasts proliferate, they produce important substances such as human dermal collagen, matrix proteins, growth factors, and cytokines. These components play a crucial role in regulating the immune response and promoting healing. The end result is a metabolically active, living dermal substitute that can effectively cover and protect the wound site. When applying the dermal substitute, it is carefully removed from its transport container and placed onto a prepared wound bed. The substitute is then secured in place using sutures or staples to ensure it remains stable during the healing process. Following this, a layered dressing is applied to the area, which typically includes a nonadherent layer to prevent sticking, a bulky layer of gauze for absorption, a compression layer to support the area, and an anti-shear layer to minimize friction. For billing purposes, CPT® Code 15360 is used for the initial application of the first 100 square centimeters or less in adults, or for 1% of total body surface area (TBSA) in infants and children. CPT® Code 15361 is then utilized for each additional 100 square centimeters in adults or each additional 1% of TBSA in infants and children, or any part thereof.
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