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Official Description

Excision, tumor, soft tissue of neck or anterior thorax, subfascial (eg, intramuscular); 5 cm or greater

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 21554 refers to the excision of a tumor located in the soft tissue of the neck or anterior thorax, specifically when the tumor is subfascial, meaning it is situated beneath the fascia, which is a layer of connective tissue. This procedure is applicable for tumors that measure 5 cm or greater. Soft tissues encompass a variety of structures, including subcutaneous fat, connective tissue, fascia, muscles, tendons, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Tumors found in these soft tissues can be either benign or malignant. Typically, benign tumors are treated through excision, while small malignant or indeterminate tumors may also be excised if they have well-defined margins. The surgical approach to excising these tumors may vary based on their location; it may involve incising the skin directly over the tumor, creating and elevating a skin flap, or making a series of incisions along natural skin creases to facilitate exposure of the tumor. Once the overlying tissue is dissected, the soft tissue mass is exposed, and the tumor is excised along with a margin of healthy tissue to ensure complete removal. In some cases, a frozen section may be performed to verify that all margins are free of tumor cells, which is a critical step in ensuring the thoroughness of the excision. After the tumor is removed, drains may be placed as necessary, and the surgical wound is typically closed in layers to promote proper healing. For smaller tumors in the subcutaneous fat or connective tissue, different codes are used, such as CPT® Code 21555 for masses less than 3 cm and CPT® Code 21552 for masses 3 cm or greater. For tumors located below the fascia, CPT® Code 21556 is designated for masses less than 5 cm, while CPT® Code 21554 is specifically for those that are 5 cm or greater, highlighting the importance of accurate coding based on tumor size and location.

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