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Official Description

Excision, tumor, soft tissue of neck or anterior thorax, subfascial (eg, intramuscular); less than 5 cm

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 21556 refers to the excision of a tumor located in the soft tissue of the neck or anterior thorax, specifically when the tumor is subfascial, meaning it lies beneath the fascia, which is a layer of connective tissue. This procedure is applicable for tumors that measure less than 5 cm in size. Soft tissues encompass a variety of structures, including subcutaneous fat, connective tissue, fascia, muscles, tendons, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. Tumors found in these soft tissues can be either benign or malignant. Typically, benign tumors are removed through excision, while small malignant or indeterminate tumors may also be excised if they have well-defined margins. The surgical approach to excising these tumors may vary based on their location; it may involve incising the skin directly over the tumor, creating and elevating a skin flap, or making a series of incisions along natural skin creases to facilitate exposure of the tumor. Once the tumor is accessed, the surrounding tissue is carefully dissected to expose the soft tissue mass, which is then excised along with a margin of healthy tissue to ensure complete removal. In some cases, a frozen section may be performed to verify that the margins are free of tumor cells, which is a separate reportable procedure. After the excision, drains may be placed as necessary, and the surgical wound is typically closed in layers to promote proper healing. For tumors located in the subcutaneous fat or connective tissue, different codes are used based on the size of the mass, with CPT® Code 21555 designated for masses less than 3 cm and CPT® Code 21552 for those 3 cm or greater. For subfascial tumors, CPT® Code 21556 is specifically used for masses less than 5 cm, while CPT® Code 21554 is reserved for those measuring 5 cm or greater. It is important to note that subfascial soft tissue tumors include those situated within muscle tissue.

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