CPT® Code 25065

The procedure described by CPT® Code 25065 refers to a biopsy of the soft tissue located in the forearm and/or wrist. A soft tissue biopsy is a medical procedure that involves the removal of a small sample of tissue from the soft tissues, which encompass various structures such as muscles, tendons, fat, blood vessels, lymph vessels, nerves, and the tissues surrounding joints. This procedure is typically performed to diagnose conditions affecting these tissues, such as infections, tumors, or other abnormalities. Prior to the biopsy, anesthesia—whether local, regional, or general—is administered based on the specific site and depth of the biopsy to ensure patient comfort. The area over the biopsy site is thoroughly cleansed to minimize the risk of infection. A careful incision is made to access the tissue, with particular attention given to protecting nearby blood vessels and nerves during the dissection process. Once the tissue sample is obtained, it is sent to a laboratory for histological evaluation, which is reported separately. After the sample is collected, the incision is closed using sutures. It is important to note that CPT® Code 25065 is specifically designated for superficial biopsies of masses or lesions found in the subcutaneous tissue, while CPT® Code 25066 is used for biopsies that require deeper dissection, such as those performed below the muscle fascia or within the muscle itself.