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Official Description

Proctosigmoidoscopy, rigid; with biopsy, single or multiple

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The procedure described by CPT® Code 45305 is known as a rigid proctosigmoidoscopy with biopsy. This medical procedure involves the insertion of a rigid endoscope into the rectal cavity, allowing the physician to visualize the rectum and the distal part of the colon, specifically the sigmoid colon. The endoscope is a flexible tube equipped with a light and camera, which provides a clear view of the internal structures. During this examination, the physician can identify abnormalities such as polyps, tumors, or signs of inflammation. Additionally, the procedure includes the collection of one or more tissue samples, known as biopsies, which are taken for further pathological examination. This is crucial for diagnosing various conditions, including colorectal cancer, inflammatory bowel disease, and other gastrointestinal disorders. The ability to obtain tissue samples during the procedure enhances diagnostic accuracy and aids in the development of an appropriate treatment plan.

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