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Official Description

Cystourethroscopy, with ureteroscopy and/or pyeloscopy; with lithotripsy (ureteral catheterization is included)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

CPT® Code 52353 refers to a specific medical procedure known as cystourethroscopy with ureteroscopy and/or pyeloscopy, accompanied by lithotripsy. This procedure is primarily utilized for the diagnosis and treatment of calculi, or stones, located within the ureters or renal pelvis. The process begins with the cleansing of the urethra using an antiseptic solution to minimize the risk of infection. A cystoscope, which can be either rigid or flexible, is then introduced through the urethra into the bladder. To enhance visualization of the bladder wall, sterile saline may be instilled into the bladder. After inspecting the bladder, the ureters are catheterized to facilitate access to the stones. A guidewire is carefully advanced through the cystoscope into the ureter, reaching the site of the calculus. The cystoscope is subsequently removed, allowing a ureteroscope to be advanced over the guidewire to the calculus site. In this procedure, the calculus is fragmented using lithotripsy, which employs either ultrasonic or electrohydraulic techniques to break the stone into smaller pieces. This fragmentation is crucial as it allows for easier retrieval of the stone fragments. Following the fragmentation process, a catheter may be placed over the guidewire into the renal pelvis, and the ureter may be irrigated to clear any remaining calculus fragments. Additionally, diagnostic or therapeutic solutions can be instilled into the ureter through the catheter, and the ureteroscope may be advanced into the renal pelvis for further examination as it is withdrawn.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The procedure described by CPT® Code 52353 is indicated for the following conditions:

  • Ureteral Calculi - Presence of stones within the ureters that may cause obstruction or pain.
  • Renal Pelvic Calculi - Stones located in the renal pelvis that require intervention for removal or fragmentation.
  • Urinary Tract Obstruction - Situations where calculi lead to blockage of urine flow, necessitating surgical intervention.
  • Recurrent Urolithiasis - Patients with a history of recurrent stone formation may require this procedure for management and prevention of future episodes.

2. Procedure

The procedure involves several critical steps to ensure effective treatment of the calculi:

  • Step 1: Preparation - The patient is positioned appropriately, and the urethra is cleansed with an antiseptic solution to reduce the risk of infection during the procedure.
  • Step 2: Cystoscope Insertion - A rigid or flexible cystoscope is introduced through the urethra into the bladder. Sterile saline may be instilled into the bladder to enhance visualization of the bladder wall.
  • Step 3: Ureteral Catheterization - After inspecting the bladder, the ureters are catheterized to gain access to the stones. A guidewire is then introduced through the cystoscope and advanced into the ureter, reaching the calculus site.
  • Step 4: Ureteroscope Advancement - The cystoscope is removed, and a ureteroscope is advanced over the guidewire to the site of the calculus for further intervention.
  • Step 5: Lithotripsy - The calculus is fragmented using lithotripsy techniques, either ultrasonic or electrohydraulic. The probe is advanced through the ureteroscope to the calculus site, where it is activated to generate shock waves that break the stone into smaller fragments.
  • Step 6: Fragment Retrieval and Irrigation - Following fragmentation, a catheter may be advanced over the guidewire into the renal pelvis. The ureter is irrigated to remove any calculus fragments, and diagnostic or therapeutic solutions may be instilled through the catheter.
  • Step 7: Final Examination - The ureteroscope may be advanced into the renal pelvis for a thorough examination as it is slowly withdrawn, ensuring that all fragments are accounted for and that the area is clear.

3. Post-Procedure

After the completion of the procedure, patients may require monitoring for any immediate complications. It is common for patients to experience some discomfort or hematuria (blood in urine) following the procedure. Post-procedure care may include hydration to facilitate the passage of any remaining stone fragments and pain management as needed. Follow-up appointments may be scheduled to assess recovery and ensure that no further intervention is necessary. Additionally, patients may be advised on dietary modifications or medications to prevent future stone formation.

Short Descr CYSTOURETERO W/LITHOTRIPSY
Medium Descr CYSTO W/URETEROSCOPY W/LITHOTRIPSY
Long Descr Cystourethroscopy, with ureteroscopy and/or pyeloscopy; with lithotripsy (ureteral catheterization is included)
Status Code Active Code
Global Days 000 - Endoscopic or Minor Procedure
PC/TC Indicator (26, TC) 0 - Physician Service Code
Multiple Procedures (51) 3 - Special payment adjustment rules for multiple endoscopic procedures apply.
Bilateral Surgery (50) 1 - 150% payment adjustment for bilateral procedures applies.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 1 - Statutory payment restriction for assistants at surgery applies to this procedure...
Co-Surgeons (62) 0 - Co-surgeons not permitted for this procedure.
Team Surgery (66) 0 - Team surgeons not permitted for this procedure.
Endoscopic Base Code 52351  Cystourethroscopy, with ureteroscopy and/or pyeloscopy; diagnostic
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Hospital Part B services paid through a comprehensive APC
ASC Payment Indicator Surgical procedure on ASC list in CY 2007; payment based on OPPS relative payment weight.
Type of Service (TOS) 2 - Surgery
Berenson-Eggers TOS (BETOS) P8E - Endoscopy - cystoscopy
MUE 1
CCS Clinical Classification 107 - Extracorporeal lithotripsy, urinary
LT Left side (used to identify procedures performed on the left side of the body)
RT Right side (used to identify procedures performed on the right side of the body)
XS Separate structure, a service that is distinct because it was performed on a separate organ/structure
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
51 Multiple procedures: when multiple procedures, other than e/m services, physical medicine and rehabilitation services or provision of supplies (eg, vaccines), are performed at the same session by the same individual, the primary procedure or service may be reported as listed. the additional procedure(s) or service(s) may be identified by appending modifier 51 to the additional procedure or service code(s). note: this modifier should not be appended to designated "add-on" codes (see appendix d).
GC This service has been performed in part by a resident under the direction of a teaching physician
58 Staged or related procedure or service by the same physician or other qualified health care professional during the postoperative period: it may be necessary to indicate that the performance of a procedure or service during the postoperative period was: (a) planned or anticipated (staged); (b) more extensive than the original procedure; or (c) for therapy following a surgical procedure. this circumstance may be reported by adding modifier 58 to the staged or related procedure. note: for treatment of a problem that requires a return to the operating/procedure room (eg, unanticipated clinical condition), see modifier 78.
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
50 Bilateral procedure: unless otherwise identified in the listings, bilateral procedures that are performed at the same session, should be identified by adding modifier 50 to the appropriate 5 digit code. note: this modifier should not be appended to designated "add-on" codes (see appendix d).
SG Ambulatory surgical center (asc) facility service
22 Increased procedural services: when the work required to provide a service is substantially greater than typically required, it may be identified by adding modifier 22 to the usual procedure code. documentation must support the substantial additional work and the reason for the additional work (ie, increased intensity, time, technical difficulty of procedure, severity of patient's condition, physical and mental effort required). note: this modifier should not be appended to an e/m service.
52 Reduced services: under certain circumstances a service or procedure is partially reduced or eliminated at the discretion of the physician or other qualified health care professional. under these circumstances the service provided can be identified by its usual procedure number and the addition of modifier 52, signifying that the service is reduced. this provides a means of reporting reduced services without disturbing the identification of the basic service. note: for hospital outpatient reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well-being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
53 Discontinued procedure: under certain circumstances, the physician or other qualified health care professional may elect to terminate a surgical or diagnostic procedure. due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. this circumstance may be reported by adding modifier 53 to the code reported by the individual for the discontinued procedure. note: this modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite. for outpatient hospital/ambulatory surgery center (asc) reporting of a previously scheduled procedure/service that is partially reduced or cancelled as a result of extenuating circumstances or those that threaten the well being of the patient prior to or after administration of anesthesia, see modifiers 73 and 74 (see modifiers approved for asc hospital outpatient use).
74 Discontinued out-patient hospital/ambulatory surgery center (asc) procedure after administration of anesthesia: due to extenuating circumstances or those that threaten the well being of the patient, the physician may terminate a surgical or diagnostic procedure after the administration of anesthesia (local, regional block(s), general) or after the procedure was started (incision made, intubation started, scope inserted, etc). under these circumstances, the procedure started but terminated can be reported by its usual procedure number and the addition of modifier 74. note: the elective cancellation of a service prior to the administration of anesthesia and/or surgical preparation of the patient should not be reported. for physician reporting of a discontinued procedure, see modifier 53.
76 Repeat procedure or service by same physician or other qualified health care professional: it may be necessary to indicate that a procedure or service was repeated by the same physician or other qualified health care professional subsequent to the original procedure or service. this circumstance may be reported by adding modifier 76 to the repeated procedure or service. note: this modifier should not be appended to an e/m service.
78 Unplanned return to the operating/procedure room by the same physician or other qualified health care professional following initial procedure for a related procedure during the postoperative period: it may be necessary to indicate that another procedure was performed during the postoperative period of the initial procedure (unplanned procedure following initial procedure). when this procedure is related to the first, and requires the use of an operating/procedure room, it may be reported by adding modifier 78 to the related procedure. (for repeat procedures, see modifier 76.)
79 Unrelated procedure or service by the same physician or other qualified health care professional during the postoperative period: the individual may need to indicate that the performance of a procedure or service during the postoperative period was unrelated to the original procedure. this circumstance may be reported by using modifier 79. (for repeat procedures on the same day, see modifier 76.)
AG Primary physician
AQ Physician providing a service in an unlisted health professional shortage area (hpsa)
AS Physician assistant, nurse practitioner, or clinical nurse specialist services for assistant at surgery
CR Catastrophe/disaster related
GA Waiver of liability statement issued as required by payer policy, individual case
GV Attending physician not employed or paid under arrangement by the patient's hospice provider
GW Service not related to the hospice patient's terminal condition
Q1 Routine clinical service provided in a clinical research study that is in an approved clinical research study
Q6 Service furnished under a fee-for-time compensation arrangement by a substitute physician or by a substitute physical therapist furnishing outpatient physical therapy services in a health professional shortage area, a medically underserved area, or a rural area
TG Complex/high tech level of care
Date
Action
Notes
2011-01-01 Changed Medium description changed.
2001-01-01 Added First appearance in code book in 2001.
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