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The procedure described by CPT® Code 65780 involves ocular surface reconstruction through the transplantation of amniotic membrane, specifically utilizing multiple layers. This surgical intervention is primarily indicated for the treatment of damage to the ocular surface, which may arise from various causes such as traumatic injury or pathological conditions affecting the eye. The amniotic membrane serves as a biological graft that provides a conducive environment for healing, acting as a basement membrane that facilitates the process of epithelialization. The amniotic membrane is sourced from a tissue bank, ensuring that it is properly prepared for transplantation. During the procedure, the physician may employ different techniques, such as inlay or overlay methods, depending on the depth and extent of the corneal defect. The inlay technique involves placing the graft directly into the defect, ensuring that the edges do not extend beyond the area of damage, while the overlay technique covers the entire corneal surface, including the limbus, to protect the underlying tissue. This protective layer not only aids in the healing process by allowing oxygen and moisture to reach the damaged epithelium but also promotes regeneration. In cases of deeper defects, a multilayered amniotic membrane graft may be utilized as a filler, which can subsequently be secured with sutures and may be covered with either an inlay or overlay graft for additional support and protection.
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