© Copyright 2026 American Medical Association. All rights reserved.
Intraoperative radiation therapy (IORT) is a specialized technique that allows for the delivery of concentrated doses of radiation directly to tumors during surgical procedures. This method is particularly advantageous as it enables the surgeon to target malignant tumors while simultaneously protecting surrounding healthy tissues and organs from radiation exposure. The procedure is performed when the tumor is accessible, allowing for precise radiation application. Common types of malignant tumors treated with IORT include those found in the gastric, pancreatic, colonic, rectal, and anal regions. Additionally, IORT is utilized for cervical, uterine, ovarian, and prostatic tumors, as well as tumors affecting the bladder, kidney, and soft tissue sarcomas. During the surgical procedure, the surgeon aims to excise as much of the tumor as possible while maneuvering healthy organs away from the radiation field to minimize collateral damage. The radiation is delivered through specialized tubes that focus the treatment directly on the tumor site. For this specific procedure, the CPT® code 77424 is used, which refers to the delivery of intraoperative radiation treatment using low energy x-ray radiation, typically administered via a portable miniature x-ray source. It is important to note that there is a separate CPT® code, 77425, designated for intraoperative electron radiation therapy (IOERT), which employs electron beams for more precise radiation delivery, further reducing the risk of damage to adjacent healthy tissues.
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