CPT® Code 77425

Intraoperative radiation therapy (IORT) is a specialized technique that allows for the delivery of high doses of radiation directly to tumors during surgical procedures. This method is particularly advantageous because it enables the surgeon to target malignant tumors while simultaneously protecting surrounding healthy tissues and organs from radiation exposure. The procedure is performed when the tumor is accessible, allowing for precise radiation application. IORT is commonly utilized for various types of malignant tumors, including those located in the gastric, pancreatic, colonic, rectal, and anal regions. Additionally, it is effective for treating cervical, uterine, ovarian, and prostatic tumors, as well as tumors of the bladder, kidney, and soft tissue sarcomas. During the IORT procedure, the surgeon first excises as much of the tumor as possible. To enhance safety, healthy organs are repositioned away from the radiation field. The radiation is then delivered through specialized tubes that focus the treatment directly on the tumor site. This targeted approach minimizes damage to adjacent healthy tissues, making IORT a valuable option in the management of certain cancers. For procedures utilizing low energy x-ray radiation, the code 77424 is applicable, while 77425 is designated for intraoperative electron radiation therapy (IOERT), which employs electron beams for more precise radiation delivery.