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Official Description

Procainamide;

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 80190 refers to a laboratory test specifically designed to measure the levels of procainamide in the blood. Procainamide is a medication classified as a cardiac antidysrhythmic agent, which means it is used to manage and treat irregular heartbeats, particularly ventricular tachycardia. This drug works by blocking abnormal electrical impulses in the heart, thereby helping to restore a normal rhythm. The test may also include the measurement of procainamide metabolites, notably n-acetyl procainamide, which can provide additional insights into the drug's efficacy and safety in the patient’s system. Regular monitoring of procainamide levels is crucial, as it helps healthcare providers ensure that the drug concentration remains within a therapeutic range, minimizing the risk of toxicity and adverse effects. It is important to note that procainamide can lead to the formation of antinuclear antibodies, which may present symptoms similar to systemic lupus erythematosus, a condition that can affect various systems in the body. The blood sample required for this test is obtained through a venipuncture, a procedure that is separately reportable. The analysis of the blood serum is conducted using a technique known as fluorescence polarization immunoassay, which is a sensitive method for detecting and quantifying drug levels in the bloodstream.

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