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Official Description

Anabolic steroids; 1 or 2

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are synthetic derivatives of the male sex hormone testosterone. The CPT® Code 80327 refers to a laboratory test specifically designed to measure the presence of 1 or 2 anabolic steroids in urine. This test is crucial for various medical and performance-related assessments. Anabolic steroids are often prescribed to address medical conditions such as male hormone deficiency syndromes, delayed puberty, and muscle wasting diseases, including those associated with cancer and AIDS. However, these substances are frequently misused by individuals seeking to enhance athletic performance or improve physical appearance. The misuse of anabolic steroids can involve practices such as 'stacking,' where multiple steroids are combined, or 'cycling,' where they are used intermittently. While anabolic steroids can effectively increase muscle mass, they also carry significant risks, including mood swings and impaired judgment. The laboratory test can identify a range of anabolic steroid compounds in urine, including but not limited to bolasterone, boldenone, and testosterone. The collection of urine samples for this test can be performed through random voiding or catheterization, and the analysis is conducted using advanced techniques such as qualitative colorimetry, high-performance liquid chromatography, or tandem mass spectrometry. The specific code 80327 is utilized when testing for 1 or 2 anabolic steroids, while code 80328 is designated for tests identifying 3 or more anabolic steroid compounds.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

Testing for Anabolic Steroids This laboratory test is indicated for the detection of anabolic steroids in individuals who may be experiencing symptoms related to anabolic steroid use or abuse, including performance enhancement in athletes or bodybuilders, and in patients with conditions that may warrant the therapeutic use of anabolic steroids.

  • Male Hormone Deficiency Syndromes This test may be performed in cases where there is a suspicion of male hormone deficiency, which can lead to various health issues.
  • Delayed Puberty The test can be indicated for adolescents who are experiencing delayed puberty, as anabolic steroids may be prescribed to stimulate development.
  • Muscle Wasting Diseases Conditions such as cancer and AIDS, which can lead to significant muscle loss, may necessitate the use of anabolic steroids, making this test relevant for monitoring treatment.
  • Performance Enhancement Athletes or individuals suspected of using anabolic steroids for performance enhancement may be tested to confirm the presence of these substances.

2. Procedure

Step 1: Sample Collection The procedure begins with the collection of a urine sample, which can be obtained through a random void or catheterization. The method of collection should be documented to ensure the integrity of the sample.

  • Step 2: Laboratory Analysis Once the urine sample is collected, it is sent to a laboratory for analysis. The testing employs qualitative colorimetry, high-performance liquid chromatography, or tandem mass spectrometry to accurately identify the presence of anabolic steroids.

3. Post-Procedure

After the laboratory analysis is completed, the results will be reported to the requesting physician or healthcare provider. It is essential to interpret the results in the context of the patient's clinical history and symptoms. If anabolic steroids are detected, further evaluation may be necessary to determine the implications of the findings, especially in cases of suspected abuse. Follow-up care may include counseling or referral to specialists for individuals found to be misusing anabolic steroids.

Short Descr ANABOLIC STEROID 1 OR 2
Medium Descr DRUG SCREEN QUANT ANABOLIC STEROID 1 OR 2
Long Descr Anabolic steroids; 1 or 2
Status Code Not Valid for Medicare Purposes
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
APC Status Indicator Code Not Recognized by OPPS when submitted on Outpatient Hospital Part B Bill Type (12x/13x)
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T2D - Other tests - other
MUE 1
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
GY Item or service statutorily excluded, does not meet the definition of any medicare benefit or, for non-medicare insurers, is not a contract benefit
Date
Action
Notes
2015-01-01 Added Added
Code
Description
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