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Official Description

Anabolic steroids; 1 or 2

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

Anabolic steroids, also known as anabolic-androgenic steroids (AAS), are synthetic derivatives of the male sex hormone testosterone. The CPT® Code 80327 refers to a laboratory test specifically designed to measure the presence of 1 or 2 anabolic steroids in urine. This test is crucial for various medical and performance-related assessments. Anabolic steroids are often prescribed to address medical conditions such as male hormone deficiency syndromes, delayed puberty, and muscle wasting diseases, including those associated with cancer and AIDS. However, these substances are frequently misused by individuals seeking to enhance athletic performance or improve physical appearance. The misuse of anabolic steroids can involve practices such as 'stacking,' where multiple steroids are combined, or 'cycling,' where they are used intermittently. While anabolic steroids can effectively increase muscle mass, they also carry significant risks, including mood swings and impaired judgment. The laboratory test can identify a range of anabolic steroid compounds in urine, including but not limited to bolasterone, boldenone, and testosterone. The collection of urine samples for this test can be performed through random voiding or catheterization, and the analysis is conducted using advanced techniques such as qualitative colorimetry, high-performance liquid chromatography, or tandem mass spectrometry. The specific code 80327 is utilized when testing for 1 or 2 anabolic steroids, while code 80328 is designated for tests identifying 3 or more anabolic steroid compounds.

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