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Official Description

Chorionic gonadotropin stimulation panel; estradiol response This panel must include the following: Estradiol, total (82670 x 2 on 3 pooled blood samples)

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

A chorionic gonadotropin stimulation panel is a diagnostic test designed to assess the response of estradiol levels in the body, particularly in the context of female fertility disorders. The procedure begins with the collection of a baseline estradiol level, which serves as a reference point for evaluating hormonal changes. Following this initial measurement, human chorionic gonadotropin (hCG) is administered to stimulate the ovaries. After the administration of hCG, additional blood samples are taken to measure estradiol levels again. These post-stimulation levels are then compared to the baseline estradiol levels to determine how effectively the ovaries are responding to the hCG stimulation. This panel specifically requires the testing of total estradiol levels twice, utilizing three pooled blood samples to ensure accuracy and reliability in the results. The outcomes of this panel can provide valuable insights into a woman's reproductive health and assist healthcare providers in diagnosing potential fertility issues.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The chorionic gonadotropin stimulation panel is indicated for the evaluation of estradiol response in women suspected of having fertility disorders. This test is particularly useful in the following scenarios:

  • Female Fertility Disorders The panel aids in diagnosing conditions that may affect a woman's ability to conceive, such as ovarian dysfunction or hormonal imbalances.

2. Procedure

The procedure for the chorionic gonadotropin stimulation panel involves several key steps to ensure accurate assessment of estradiol response:

  • Step 1: Baseline Estradiol Measurement Initially, a blood sample is collected to measure the baseline level of estradiol. This measurement is crucial as it establishes a reference point for evaluating the hormonal response following hCG administration.
  • Step 2: Administration of Human Chorionic Gonadotropin (hCG) After obtaining the baseline estradiol level, hCG is administered to stimulate the ovaries. This hormone mimics the natural luteinizing hormone (LH) surge that triggers ovulation, thereby promoting estradiol production.
  • Step 3: Post-Stimulation Estradiol Measurement Following the administration of hCG, additional blood samples are collected to measure estradiol levels again. This step is performed to assess how the ovaries respond to the stimulation provided by hCG.
  • Step 4: Comparison of Estradiol Levels The estradiol levels obtained from the post-stimulation samples are compared to the baseline levels. This comparison helps determine the effectiveness of the ovarian response to hCG and provides insights into the patient's fertility status.

3. Post-Procedure

After the completion of the chorionic gonadotropin stimulation panel, patients may be advised to wait for the results, which will typically be available after the analysis of the blood samples. It is important for healthcare providers to review the estradiol levels in conjunction with other clinical findings to make informed decisions regarding further diagnostic or therapeutic interventions. Patients may also be monitored for any potential side effects related to hCG administration, although significant adverse effects are uncommon. Follow-up appointments may be scheduled to discuss the results and any necessary next steps in the evaluation or treatment of fertility issues.

Short Descr TOT ESTRADIOL RESPONSE PANEL
Medium Descr CHORNC GONAD STIMJ PNL TOTAL ESTRADIOL RESPONSE
Long Descr Chorionic gonadotropin stimulation panel; estradiol response This panel must include the following: Estradiol, total (82670 x 2 on 3 pooled blood samples)
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 235 - Other Laboratory
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
Date
Action
Notes
2021-01-01 Changed Code changed.
2009-01-01 Changed Code description changed.
1994-01-01 Added First appearance in code book in 1994.
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