CPT® Code 80414

Chorionic gonadotropin stimulation panel; testosterone response This panel must include the following: Testosterone (84403 x 2 on 3 pooled blood samples)

The CPT® Code 80414 refers to a specific laboratory test known as the chorionic gonadotropin stimulation panel, which is designed to assess the testosterone response in patients. This panel is particularly relevant for evaluating infants who present with ambiguous genitalia and palpable gonads, as well as males experiencing delayed puberty or undescended testes. Additionally, it serves to confirm the presence of active testicular tissue. The test involves measuring the baseline level of testosterone prior to any stimulation and then assessing the testosterone levels following the administration of an evocative agent, specifically human chorionic gonadotropin (hCG). The procedure begins with the collection of three blood samples, which are drawn 15-20 minutes apart and pooled together to establish a baseline testosterone level. After the baseline measurement, an intramuscular or subcutaneous injection of 5,000 units of hCG is administered. Following this injection, a post-response sample is collected three days later, again involving three blood samples drawn 15-20 minutes apart and pooled for analysis. The serum or plasma obtained from these samples is then tested using a quantitative electrochemiluminescent immunoassay, providing a detailed evaluation of the testosterone response to the stimulation.