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Official Description

Lipoprotein, direct measurement; VLDL cholesterol

© Copyright 2026 American Medical Association. All rights reserved.

Common Language Description

The CPT® Code 83719 refers to the direct measurement of very low density lipoprotein (VLDL) cholesterol in a blood sample. This procedure is essential for assessing lipoprotein levels, which are critical in understanding lipid metabolism and cardiovascular health. Lipoproteins are complex biochemical structures composed of lipid molecules, such as cholesterol and triglycerides, bound to proteins. They play a vital role in transporting fats throughout the body via the bloodstream. The size and density of lipoproteins can vary significantly; they range from large, less dense particles, where fat predominates, to smaller, denser particles, where protein is more prevalent. Lipoproteins can be classified based on their origin: exogenous lipoproteins are derived from dietary fats, while endogenous lipoproteins are synthesized in the liver. Among the various types of lipoproteins, low density lipoproteins (LDL) are particularly noteworthy due to their association with cardiovascular disease (CVD). Within the LDL category, there are subclasses that differ in size and density, with small dense LDL (sdLDL) being particularly concerning. SdLDL is linked to a higher risk of atherosclerosis and is a significant contributor to inflammatory processes associated with CVD. Conversely, high density lipoproteins (HDL) are beneficial as they assist in the removal of cholesterol from the bloodstream, thereby reducing the risk of atherosclerosis and CVD. The direct measurement of lipoproteins, such as VLDL cholesterol, is performed using specific laboratory tests that provide a more accurate assessment than calculations based on total cholesterol, HDL, and triglycerides. This procedure requires a blood sample, which is typically obtained through venipuncture. The results from this test can provide valuable insights into a patient's lipid profile and overall cardiovascular risk, guiding further clinical decisions and interventions.

© Copyright 2026 Coding Ahead. All rights reserved.

1. Indications

The direct measurement of very low density lipoprotein (VLDL) cholesterol using CPT® Code 83719 is indicated for various clinical scenarios, particularly when assessing lipid metabolism and cardiovascular risk. The following conditions may warrant this procedure:

  • Hyperlipidemia - Patients presenting with elevated lipid levels may require VLDL measurement to evaluate their lipid profile and determine appropriate management strategies.
  • Cardiovascular Disease (CVD) Risk Assessment - Individuals at risk for CVD, including those with a family history of heart disease or other risk factors, may benefit from VLDL cholesterol measurement to better understand their cardiovascular health.
  • Monitoring Treatment Efficacy - Patients undergoing treatment for dyslipidemia may need periodic VLDL measurements to assess the effectiveness of their therapy and make necessary adjustments.
  • Metabolic Syndrome Evaluation - In patients diagnosed with metabolic syndrome, measuring VLDL cholesterol can provide additional insights into their lipid abnormalities and overall metabolic health.

2. Procedure

The procedure for measuring very low density lipoprotein (VLDL) cholesterol involves several key steps to ensure accurate results. The following outlines the procedural steps:

  • Step 1: Patient Preparation - Prior to the blood draw, the patient may be instructed to fast for a specified period, typically 9 to 12 hours, to ensure that the lipid levels are not influenced by recent food intake.
  • Step 2: Venipuncture - A qualified healthcare professional performs venipuncture to obtain a blood sample. This involves inserting a needle into a vein, usually in the arm, to collect the necessary volume of blood into a sterile collection tube.
  • Step 3: Laboratory Analysis - The collected blood sample is sent to a laboratory where it undergoes analysis. The laboratory utilizes specific methodologies to directly measure the concentration of VLDL cholesterol in the serum or plasma.
  • Step 4: Result Interpretation - Once the analysis is complete, the laboratory provides the results, which are interpreted by the healthcare provider. The VLDL cholesterol levels are assessed in conjunction with other lipid parameters to evaluate the patient's cardiovascular risk and guide treatment decisions.

3. Post-Procedure

After the procedure, patients may experience minimal discomfort at the venipuncture site, which typically resolves quickly. There are no specific post-procedure care requirements for this test; however, patients are generally advised to resume their normal activities immediately. The healthcare provider will discuss the results with the patient during a follow-up appointment, where they will review the implications of the VLDL cholesterol levels in the context of the patient's overall health and any necessary lifestyle or medication adjustments.

Short Descr ASSAY OF BLOOD LIPOPROTEIN
Medium Descr LIPOPROTEIN DIRECT MEASUREMENT VLDL CHOLESTEROL
Long Descr Lipoprotein, direct measurement; VLDL cholesterol
Status Code Statutory Exclusion (from MPFS, may be paid under other methodologies)
Global Days XXX - Global Concept Does Not Apply
PC/TC Indicator (26, TC) 9 - Not Applicable
Multiple Procedures (51) 9 - Concept does not apply.
Bilateral Surgery (50) 9 - Concept does not apply.
Physician Supervisions 09 - Concept does not apply.
Assistant Surgeon (80, 82) 9 - Concept does not apply.
Co-Surgeons (62) 9 - Concept does not apply.
Team Surgery (66) 9 - Concept does not apply.
Diagnostic Imaging Family 99 - Concept Does Not Apply
CLIA Waived (QW) No
APC Status Indicator Conditionally packaged laboratory tests
Type of Service (TOS) 5 - Diagnostic Laboratory
Berenson-Eggers TOS (BETOS) T1H - Lab tests - other (non-Medicare fee schedule)
MUE 1
CCS Clinical Classification 233 - Laboratory - Chemistry and Hematology
GW Service not related to the hospice patient's terminal condition
90 Reference (outside) laboratory: when laboratory procedures are performed by a party other than the treating or reporting physician or other qualified health care professional, the procedure may be identified by adding modifier 90 to the usual procedure number.
59 Distinct procedural service: under certain circumstances, it may be necessary to indicate that a procedure or service was distinct or independent from other non-e/m services performed on the same day. modifier 59 is used to identify procedures/services, other than e/m services, that are not normally reported together, but are appropriate under the circumstances. documentation must support a different session, different procedure or surgery, different site or organ system, separate incision/excision, separate lesion, or separate injury (or area of injury in extensive injuries) not ordinarily encountered or performed on the same day by the same individual. however, when another already established modifier is appropriate it should be used rather than modifier 59. only if no more descriptive modifier is available, and the use of modifier 59 best explains the circumstances, should modifier 59 be used. note: modifier 59 should not be appended to an e/m service. to report a separate and distinct e/m service with a non-e/m service performed on the same date, see modifier 25.
XU Unusual non-overlapping service, the use of a service that is distinct because it does not overlap usual components of the main service
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2006-01-01 Changed Code description changed.
Pre-1990 Added Code added.
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