CPT® Code 84153

Prostate specific antigen (PSA) is a protein produced by normal prostate cells and is found in the serum. The measurement of PSA is significant in the context of prostate health, as it exists in two forms: free PSA and complexed PSA. The total PSA measurement, represented by CPT® Code 84153, encompasses both of these forms. Elevated levels of total PSA can indicate various prostate conditions, including benign prostatic hyperplasia (BPH), acute bacterial prostatitis, and prostate cancer. While total PSA is a useful tool for screening for prostate cancer and monitoring treatment responses in patients already diagnosed with the disease, it is important to note that it cannot definitively diagnose prostate cancer on its own. The total PSA measurement is often used in conjunction with other tests, such as free PSA measurement (CPT® Code 84154), to provide a more comprehensive assessment of prostate health and to help differentiate between benign and malignant conditions.